Dr. Yu started his PhD research in the Institute of Biophysics, Chinese Academy of Sciences in 2003. During the four years of auditory research, He found that most current auditory research made the subjects as passive listeners and very few experiments were carried out when subjects actively responded to the sound. In order to bring behavior analysis to the auditory neurophysiology, He moved to Dr. Dora Angelaki’s lab in the US as a postdoc from December, 2009 to May, 2014, where cognitive function was accessed with behaving nonhuman primates. Dr. Yu was enrolled in Zhejiang University as PI in June, 2014, where he is going to merge the neurophysiologic techniques and behavior analysis in the auditory system with the topics focusing on decision making and sleep.
Determining what is going on in the real world from neuronal spiking patterns, which is the process of decoding, represents an important challenge for the brain: How do the properties of a few neurons or populations of neurons relate to and perhaps account for sensory perception? The issue of decoding has received immense attention in the fields of computational neuroscience, motor prosthesis and brain-machine-interface, as well as sensory coding for perception in other physiological systems. Unfortunately, with the exception of less than a handful of studies, such concepts have seldom been applied to the auditory system. In the last decade, only 0.3% of pubmed-cited manuscripts that examined audition or hearing focused on the interaction between the auditory cortex, behavior, and neural activity, thus it is timely to bring the gap between auditory system and the other sensor systems.
That is our goal now:
1) To seek the neuronal correlates with the sound related dicision making such as sound detection/ discrimination and sound location.
2) To seek the origin of these correlates and the origin of the psychological limit.
3) To seek how attention, adaptation and emotion (especially depression) affect the decision making and the neuronal mechanism underlying the effects.