Movement control and Navigation

Xinjian Li

Principle Investigator

Email: lxjbio@zju.edu.cn

Laboratory of Movement Control and Navigation 


Lab Intertests:

Fine movement control; Spatial Navigation; Brain-machine Interface; Movement-related diease


Introduction

Dr. Xinjian Li received his Ph.D. degree in Institute of Neuroscience, Chinese Academy of Sciences. Then he took three round of Post-doctoral training in Hong Kong polytechnic University (Hong Kong), Johns Hopkins University(USA) and National institute of Health (NIH, USA). During his research, he used Drosophila, mouse, rat, marmoset and macaque to study fine movement control, neuropathic pain, schizophrenia, decision making, sleep and learning & memory. In his Post-doctoral training in NIH, he made great achievement in developing single-cell calcium imaging methods in freely behavior animals. Then he studied the corticospinal neurons in movement control (Cell, 2017) and neuropathic pain(Nature,2018). In 2019, he continues his reach on Fine Motor Control and Navigation in Zhejiang University. 

李新建博士于2010年于中国科学院神经所获得博士学位,随后分别在香港理工大学、美国约翰霍普金斯大学和美国国立健康研究所进行研究工作。他丰富的研究经历使他利用果蝇、小鼠、大鼠、狨猴及猕猴在学习记忆、运动控制、神经痛机精神分裂症等方向进行科学研究。

     近2年间,李新建博士发表文章4篇,其中2篇第一作者的文章发表于神经科学的顶级期刊《Nature》和《Cell》,这些工作揭示皮质脊髓束神经元对精细连续运动控制的模块化和平行化机制及皮层脊髓束神经元在神经痛中的作用。这些研究工作对脑机接口的改进和神经痛的治疗有很好的理论指导作用。同时李新建博士在自由活动的动物上首次建立了皮层浅层神经元单细胞水平的钙成像活动的方法。

2019年初,李新建博士作为独立的研究员加入浙江大学医学院附属第二医院及系统神经及认知科学研究所。其实验室以小型小鼠和非人灵长类动物狨猴为模式动物,通过对皮层神经元进行单细胞水平钙成像的办法来研究肢体运动的精细控制、语言产生、空间导航、及相关疾病的神经机制。