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UHF MRI 2017

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INTERDISCIPLINARY INSTITUTE OF NEUROSCIENCE AND TECHNOLOGY

                 How success feeds success -- mouse study may tell how


Getting to the top of social hierarchy is often not a matter of body size or brute strength, but rather determined by intrinsic mental factors such as grit, as well as extrinsic factors such as history of winning. For example, social dominance can be reinforced by a phenomenon known as the “winner effect”, whereby animals increase their probability of victory after previous winnings. However, the neural mechanism that mediates these intrinsic and extrinsic factors was poorly understood. On July 14, 2017, Professor Hailan Hu’s research group from Zhejiang University in China published a research article entitled "Winning History Remodels Thalamo-PFC Circuit to Reinforce Social Dominance" (Zhou and Zhu et al.) to address this problem in the journal Science.

 

Six years earlier, Hu’s group reported using the dominance tube test to measure social hierarchy status in mice (Wang et al., Science, 2011). They discovered that by changing the strength of synaptic connections (through which brain cells communicate with each other) in a brain region called the medial prefrontal cortex (mPFC), they can make mice climb up or move down the social ladder. However, the acute requirement of mPFC during ongoing social competition and the upstream neural circuit that regulates mPFC activity in dominance behaviors were essentially unknown. It was also unclear whether the “winner effect” can be generalized, in other words, whether dominance acquired in one type of competition can transfer to another behavioral type.

 

In the current study, graduate student Tingting Zhou, Hong Zhu and Zhengxiao Fan from Hailan Hu’s lab built on their earlier work and addressed the above questions by applying cutting-edge techniques including in vivo single-unit electrophysiology recording, optogenetics, chemicogenetics and in vivo optic LTP and LTD. Several discoveries were made:

 

1. They established that activation of dorsal medial prefrontal cortex (dmPFC) is both necessary and sufficient to induce instant (within seconds) winning in dominance contests. Specifically, by optogenetically isolating a synaptic input from mediodorsal thalamus (MDT) to dmPFC, they were able to selectively manipulate synapses driven by this input and establish a causal relationship between the activity of the MDT-dmPFC circuit and mental-effort-based dominance behavior. Importantly, mPFC activation does not seem to boost dominance by enhancing basal aggression level or physical strength, but rather by initiating and maintaining more effortful behaviors during social competition.

 

2. With in vivo optogenetic LTP and LTD experiments, they provided strong evidence that synapses in the MDT-dmPFC pathway may encode previous winning/losing history, identifying the first neural circuit for mediating the “winner effect” in mammals.

 

3. They discovered and provided neural circuit mechanism for a generalized form of “winner effect”, where dominance acquired in one behavior can transfer to another type of social contest. Previous studies of the “winner effect” were restricted to the impact of winning on the same behavioral paradigm. Given that animals are dealing with different forms of competitions in setting up the social hierarchy, the generalized “winner effect” that Zhou et al. describe here is of considerable evolutionary significance. For example, it may allow a monkey who succeeds in fighting for bananas earlier to occupy a more comfortable resting spot later. Such reciprocal reinforcement between winning in different behavioral paradigms would help to accelerate the establishment of a stable dominance hierarchy.

 

Through this work, Hu’s group identifies for the first time the MDT-dmPFC circuit as an important neural substrate mediating both the intrinsic (mental strength) and extrinsic (history of winning) factors for social hierarchy determination. As the lack of social competitive drive prevents individuals from realizing their potential and is a hallmark of many psychiatric disorders, their results will shed important light on treating the motivational defects in these psychiatric diseases.

 

This work was carried out by graduate students Tingting Zhou, Hong Zhu and Zhengxiao Fan et al., under the supervision of Dr. Hailan Hu. The study was completed at the Zhejiang University Interdisciplinary Institute of Neuroscience and Technology (ZIINT) and Center for Neuroscience, School of Medicine at Zhejiang University, Hangzhou, China.

 20170718080545846.jpg.png596c5b4eafe15.jpg

Author: Zhengxiao Fan, Hong Zhu, Hailan Hu, Tingting Zhou


2017-08-14 READ MORE

Dr. Xiongjie Yu's group published new Paperin Elife


Jean Laurens#, Sheng Liu#, Xiong-Jie Yu#, Raymond Chan1, David Dickman1, Gregory C DeAngelis5, Dora E Angelaki, Transformation of spatiotemporal dynamics in the macaque vestibular system from otolith afferents to cortex.Elife2017


Abstract:

Sensory signals undergo substantial recoding when neural activity is relayed from sensors through pre-thalamic and thalamic nuclei to cortex. To explore how temporal dynamics and directional tuning are sculpted in hierarchical vestibular circuits, we compared responses of macaque otolith afferents with neurons in the vestibular and cerebellar nuclei, as well as five cortical areas, to identical three-dimensional translational motion. We demonstrate a remarkable spatio-temporal transformation: otolith afferents carry spatially aligned cosine-tuned translational acceleration and jerk signals. In contrast, brainstem and cerebellar neurons exhibit non-linear, mixed selectivity for translational velocity, acceleration, jerk and position. Furthermore, these components often show dissimilar spatial tuning. Moderate further transformation of translation signals occurs in the cortex, such that similar spatio-temporal properties are found in multiple cortical areas. These results suggest that the first synapse represents a key processing element in vestibular pathways, robustly shaping how self-motion is represented in central vestibular circuits and cortical areas.


图片1.png

Online Paperhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226653/


2017-05-18 READ MORE

The NSFC major research program  "neural circuits of emotion and memory"  international symposium in 2017


(28 October, 2017 - 3  November 2017,Hangzhou)

The NSFC major research program  "neural circuits of emotion and memory"  international symposium will be held on November 2, 2017 - November 3 in hangzhou. This meeting sponsored by the national natural science fund committee, neuroscience research center of zhejiang university.


The meeting will be held from November 2 to November 13, 2017, and the purpose of the meeting was to summarize the implementation of the 2017 major research projects on the basis of the "neural circuits of emotion and memory". The process of the problems encountered and for the next stage of the project layout and project applications to guide the promotion of domestic and foreign emotional and memory of the neural loop basic research areas of international exchanges and cooperation, concise research direction, to explore the future development trend of the field And the scientific issues of common interest. The theme of this year's International Symposium is the basis of emotional and cognitive neural loops, which will be invited by international and domestic experts in the field.
1.Academic committee
Chairman: Shumin Duan
Committee: Aike Guo, Yi Rao, Jiangning Zhou, Qingming Luo, Lanqun Mao, Beisha Tang, Zhijun  Zhang, Xiaoming Li  

2. Organize committee
Chairman: Anna Wang Roe
Executive chairman: Zhong Chen, Hailan Hu
Secretary: Jingwei Zhao, Yang Wei
Secretary: Yu-hui Liu, Li Liu

3.Registration fee
Registration fee and category: travel and accommodation themselves, the meeting will receive a certain registration fee (including meals). If you are sure to attend only the training course, do not participate in the "annual summary of major research projects" and "international academic exchange meeting", please be sure to indicate in the receipt of the participants.

4. Meeting Schedule:
1) Annual Summary Meeting on Major Research Projects and International Symposium
November 1, 2017 14: 00-18: 00 Registration, 2 to 3 days all day meeting
2) training courses
October 28, 2017 14: 00-18: 00 Registration, 29 to 1 day training


5.Accommodation:
1) "Annual Summary Meeting of Major Research Projects" and "International Seminar" Meeting Venue: Jun Shang Hotel, Zhejiang Jun Shang Hotel. Address: West Lake District, Hangzhou City, three pier town lights Street 539, near the town of North Road Tel: 0571-88006868
2) Training Venue: Zijingang Campus Medical College, Zhejiang University. In accordance with the order of payment, the quota of 70 people.


6.Contact:
Contact E-mail: 0915056@zju.edu.cn
Meeting Contact: Yuhui Liu, Neuroscience Research Center, Zhejiang University, Tel: 18158515080
Conference related website: http: //www.emnc.net/


7.Remittance Information:
Name: Zhejiang Institute of Neuroscience
Bank: 10450000000531972
Bank account: Huaxia Bank Hangzhou Branch
Note: Please pay attention to the major research plan, name, invoice header information when sending money

Speaker Schedule

Domestic Experts

  Time

Institution


  Speakers

2017.11.2

 

Zhejiang University

Anna Wang Roe

Zhejiang University

Hailan Hu

Shanghai Institutes for Biological Sciences

Zilong Chou

Shanghai Institutes for Biological Sciences

Xu Zhang

2017.11.3

 

University of Science and Technology of China

Guoqiang Bi

Zhejiang University

Zhong Chen

Institute of Automation of Academia Sinica

Tianzai Jiang

Beijing Normal University

Wu Li

·    Peking University

Lin Lu

National Institute of Biological Sciences

Minmin Luo

Fudan University

Lan Ma

Institute of Biophysics Academy of Sciences

Xiaoqun Wang

University of Chinese Academy of Sciences

Fuqiang Xu

Fudan University

Yongchun Yu

Huazhong University of Science and Technology

Shaoqun Zeng

Beijing Normal University

Xiaohui Zhang

Nanjing Medical University

Yadong Zhu

Foreign Experts

  Time

Institution


  Speakers

2017.11.2

 

Cold Spring Harbor Laboratory

Bo Li

University of California at Los Angeles

Jonathan Flint

Cold Spring Harbor Laboratory

Josh Huang

Northwestern University

Lee Miller

Mount Sinai

Ming-hu Han

Massachusetts Institute of   Technology

Mriganka Sur

U Chicago

Nicho Hatsopoulos

U Chicago

Sliman Bensmaia

Arizona State University

Steven Helms Tillery

University of Ottawa

Xia Zhang

2017-09-26 READ MORE
2017-07-07 READ MORE

      浙江大学求是高等研究院 关于举办2017年优秀大学生夏令营通知

Release Date: May 19th, 2017        Editor:Ming Xiong                            

为给全国高校优秀大学生创建神经科学、生物医学、信息科学等交叉学科学术交流平台,提供与该领域专家教授交流的机会,帮助青年学生更好地了解当前学科发展热点问题,浙江大学求是高等研究院定于2017年7月5日-9日在景色宜人的杭州举办2017年优秀大学生夏令营。

浙江大学求是高等研究院成立于2006年10月,由香港著名企业家、浙江大学资深学长查济民名誉博士和刘璧如女士资助建立,属校设直属科研机构,享受学校的特殊政策。研究院充分发挥生物医学工程、神经科学、信息科学和临床医学等多学科交叉优势,围绕神经工程、前沿交叉领域进行了探索性研究,取得了一系列丰硕的成果。每年定期举办的西湖学术论坛(FINT)、超高场磁共振成像技术研讨会等国际学术会议,提供了与国内外顶尖专家交流及了解前沿技术热点的学术平台;提供出国学术访问与联合学位培养,开拓国际视野建立国际化人才队伍;并拥有全球顶尖科研设备,全国唯一主动屏蔽式7T超高场磁共振系统(MRI),掌握超高场磁共振成像技术,是该领域科技前沿与应用的焦点;每周邀请国内外学者演讲与访问,加强了各研究单位间的学术交流与合作。

依托于生物医学工程、光学工程和计算机应用技术等国家级重点学科和国家级及省部级重点实验室,求是高等研究院着力培养生物、医学、工程技术等领域交叉研究的创新型交叉学科人才。2018年求是高等研究院研究生招生学科为:生物医学工程、神经生物学、计算机科学、临床医学(精神病学、外科学、影像医学与核医学等)。学生将根据主修专业获得相应的学术学位。欢迎考生跨学科报考,相关专业包括:生物医学工程、计算机科学、基础医学、光学工程,电子信息技术、生物技术、材料科学、化学工程、临床医学等。

一、夏令营简介

本夏令营旨在促进高校优秀大学生间的交流互动,加强神经生物学、生物医学工程和信息电子工程等专业与国内高水平大学相关院系的联系,特别是使这些学校的学生能够进一步认识浙大、了解浙大求是高等研究院。本次活动为期五天,内容包括专家讲座、实验室参观与操作、知识竞赛、师生互动等精彩活动。

第一天:开营式、实验室参观、师生座谈。

第二天:专家讲座、实验室参观、知识竞赛。

第三天:专家讲座、实验室参观、实验操作训练。

第四天:学员论坛、师生互动、晚会。

第五天:闭营式。

二、申请条件

1、具有浓厚的科学研究兴趣,有志于神经生物学、生物医学工程和信息电子工程等专业,有较强或潜在的研究能力, 并有继续深造意向。

2、英语水平较好,学习成绩优秀。本科期间成绩总排名“985”院校在本专业30%以内,“211”院校在前20%以内,对有出色科研成果或特长学生学习成绩标准可适当放宽。

3、专业要求:神经生物学、生物医学工程、电子、电气、控制类相关专业(包括医学、药学、数学、物理、化学、生物等)三年级本科生(2018届毕业生)。

三、资助条件

1、参加暑期夏令营的学生必须遵守浙江大学的相关规定,按照统一的安排参加活动。

2、夏令营不收注册费。浙江大学求是高等研究院将为营员免费提供交通、住宿、保险以及相关活动的资助,包括营员来杭州的交通费(按浙大本科生实习费用规则报销,车票信息与学校或家庭所在地乘车区间相符者有效)。

3、夏令营活动以外的时间由营员自行安排,所产生的费用由营员自理。

四、申请方式

报名截止时间:2017年6月23日下午5点整,学生需要网上申报(申请材料需PDF格式),不接受纸质申请材料。申请材料包括:本科成绩单1份(须加盖院系或学校教务处公章),总成绩排名1份(须加盖院系或学校教务处公章),CET六级或其他英语考试的成绩证明1份及其它获奖材料(如已发表论文、各类获奖证书等)。报名网址:https://st3529873.huoban.com/share/3696463/KG2pKKe5H1M1HuqexBpjG5Ga2KxpHUMsUg2Ugg2d/205304/list


 

报名二维码:            

 

 

入营交流群二维码:         


五、材料审核及录取

1、夏令营申请工作即日进行,专家小组审核相关材料后,择优录取30名营员,由浙江大学求是高等研究院发录取通知,录取名单将于6月26日前在求是高等研究院网站(http://www.qaas.zju.edu.cn)及系统神经与认知科学研究所网站(http://www.ziint.zju.edu.cn/index.php/Index/Cindex.html)公布,不再另行通知。

2、确认参加者请在6月28日前将回执返回,

3、具体报道时间和地点待营员回执返回后通知。

凡参加夏令营者,须随身携带以下材料:

1)身份证及身份证复印件;

2)申请表中所涉及的相关证书证明材料的原件及复印件;

3)英语四六级成绩原件及复印件;

4)本科学习成绩总表原件。


     注:由于实验室属于高洁净环境,确认参加者须进行结核菌测试,可经由皮测、胸片或血液等不同方法取得,须于7月1日前寄回电子版结核菌测试结果。

 

 



2017-05-19 READ MORE
2017-07-24 READ MORE
2017-05-05 READ MORE

          How success feeds success -- mouse study may tell how


Getting to the top of social hierarchy is often not a matter of body size or brute strength, but rather determined by intrinsic mental factors such as grit, as well as extrinsic factors such as history of winning. For example, social dominance can be reinforced by a phenomenon known as the “winner effect”, whereby animals increase their probability of victory after previous winnings. However, the neural mechanism that mediates these intrinsic and extrinsic factors was poorly understood. On July 14, 2017, Professor Hailan Hu’s research group from Zhejiang University in China published a research article entitled "Winning History Remodels Thalamo-PFC Circuit to Reinforce Social Dominance" (Zhou and Zhu et al.) to address this problem in the journal Science.

 

Six years earlier, Hu’s group reported using the dominance tube test to measure social hierarchy status in mice (Wang et al., Science, 2011). They discovered that by changing the strength of synaptic connections (through which brain cells communicate with each other) in a brain region called the medial prefrontal cortex (mPFC), they can make mice climb up or move down the social ladder. However, the acute requirement of mPFC during ongoing social competition and the upstream neural circuit that regulates mPFC activity in dominance behaviors were essentially unknown. It was also unclear whether the “winner effect” can be generalized, in other words, whether dominance acquired in one type of competition can transfer to another behavioral type.

 

In the current study, graduate student Tingting Zhou, Hong Zhu and Zhengxiao Fan from Hailan Hu’s lab built on their earlier work and addressed the above questions by applying cutting-edge techniques including in vivo single-unit electrophysiology recording, optogenetics, chemicogenetics and in vivo optic LTP and LTD. Several discoveries were made:

 

1. They established that activation of dorsal medial prefrontal cortex (dmPFC) is both necessary and sufficient to induce instant (within seconds) winning in dominance contests. Specifically, by optogenetically isolating a synaptic input from mediodorsal thalamus (MDT) to dmPFC, they were able to selectively manipulate synapses driven by this input and establish a causal relationship between the activity of the MDT-dmPFC circuit and mental-effort-based dominance behavior. Importantly, mPFC activation does not seem to boost dominance by enhancing basal aggression level or physical strength, but rather by initiating and maintaining more effortful behaviors during social competition.

 

2. With in vivo optogenetic LTP and LTD experiments, they provided strong evidence that synapses in the MDT-dmPFC pathway may encode previous winning/losing history, identifying the first neural circuit for mediating the “winner effect” in mammals.

 

3. They discovered and provided neural circuit mechanism for a generalized form of “winner effect”, where dominance acquired in one behavior can transfer to another type of social contest. Previous studies of the “winner effect” were restricted to the impact of winning on the same behavioral paradigm. Given that animals are dealing with different forms of competitions in setting up the social hierarchy, the generalized “winner effect” that Zhou et al. describe here is of considerable evolutionary significance. For example, it may allow a monkey who succeeds in fighting for bananas earlier to occupy a more comfortable resting spot later. Such reciprocal reinforcement between winning in different behavioral paradigms would help to accelerate the establishment of a stable dominance hierarchy.

 

Through this work, Hu’s group identifies for the first time the MDT-dmPFC circuit as an important neural substrate mediating both the intrinsic (mental strength) and extrinsic (history of winning) factors for social hierarchy determination. As the lack of social competitive drive prevents individuals from realizing their potential and is a hallmark of many psychiatric disorders, their results will shed important light on treating the motivational defects in these psychiatric diseases.

 

This work was carried out by graduate students Tingting Zhou, Hong Zhu and Zhengxiao Fan et al., under the supervision of Dr. Hailan Hu. The study was completed at the Zhejiang University Interdisciplinary Institute of Neuroscience and Technology (ZIINT) and Center for Neuroscience, School of Medicine at Zhejiang University, Hangzhou, China.

 

596c5b4eafe15.jpg

Author: Zhengxiao Fan, Hong Zhu, Hailan Hu, Tingting Zhou



2017-08-14 READ MORE

Dr. Xiongjie Yu's group published in Elife


Jean Laurens#, Sheng Liu#, Xiong-Jie Yu#, Raymond Chan1, David Dickman1, Gregory C DeAngelis5, Dora E Angelaki, Transformation of spatiotemporal dynamics in the macaque vestibular system from otolith afferents to cortex.Elife2017


Abstract:

Sensory signals undergo substantial recoding when neural activity is relayed from sensors through pre-thalamic and thalamic nuclei to cortex. To explore how temporal dynamics and directional tuning are sculpted in hierarchical vestibular circuits, we compared responses of macaque otolith afferents with neurons in the vestibular and cerebellar nuclei, as well as five cortical areas, to identical three-dimensional translational motion. We demonstrate a remarkable spatio-temporal transformation: otolith afferents carry spatially aligned cosine-tuned translational acceleration and jerk signals. In contrast, brainstem and cerebellar neurons exhibit non-linear, mixed selectivity for translational velocity, acceleration, jerk and position. Furthermore, these components often show dissimilar spatial tuning. Moderate further transformation of translation signals occurs in the cortex, such that similar spatio-temporal properties are found in multiple cortical areas. These results suggest that the first synapse represents a key processing element in vestibular pathways, robustly shaping how self-motion is represented in central vestibular circuits and cortical areas.

图片1.png

Online Paperhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226653/

2017-05-19 READ MORE

 Dr.Lixia Gao's group published new paper in Neuroscience


Lixia Gao*, Xinjian Li, Wenwei Yang and Xinde Sun. Modulation of azimuth tuning plasticity in rat primary auditory cortex by medial prefrontal cortex. Neuroscience, 2017 April 7.


Abstract:

Neurons in the primary auditory cortex (A1) of adult animals exhibit short-term plasticity of frequency selectivity and tonotopic organization in behavioral contexts ranging from classical conditioning to attention tasks. However, it is still largely unknown whether short-term plasticity of spatial tuning takes place in A1 of adult animals and whether this spatial turning plasticity in A1 of adults is mediated by medial prefrontal cortex (mPFC) as there are reciprocal connection between mPFC and auditory cortex (AC). In the present study, we used extracellular recordings to test whether azimuth tuning in A1 of anesthetized rats can be reshaped by repeated sound stimuli at neurons’ nonpreferred azimuth. We also identified whether and how such A1 azimuth tuning plasticity was modulated by the neural activities of mPFC. Our results showed that A1 neurons in adult rats have azimuth tuning plasticity when repeated acoustic stimuli were delivered at the azimuth with a deviation by less than 15 from the best azimuth (BA). The BA shifted toward the exposure azimuth when repeated acoustic stimuli were played for 20–60 min and plasticity decayed within one hour. The less the angle deviated from the BA, the shorter exposure time and longer decay time were required to induce azimuth tuning plasticity. Neural activity in mPFC modulated azimuth tuning plasticity of A1 neurons as reflected by the shorter induction time when mPFC was activated by focal electrical stimulation and the longer induction time when mPFC was inactivated by drug application. Our results suggest that spatial location selectivity in A1 neurons remains plastic in mature animals and that short-term plasticity of spatial tuning can be modulated by the neural activities of mPFC.

原文链接:http://dx.doi.org/10.1016/j.neuroscience.2017.01.046


图片3.png


2017-05-11 READ MORE

浙江大学求是高等研究院白瑞良课题组研究助理(技术员)招聘启事


根据实验室科研工作需要,浙江大学求是高等研究院系统神经与认知科学研究所“定量脑影像”课题组(白瑞良课题组)拟公开招聘研究助理(技术员)2名。

一、研究简介

本实验室从事新型脑影像技术方面的研究,主要针对中枢神经系统疾病诊断以及脑科学与认知的需求,开发高级磁共振成像序列及磁共振信号分析模型。 主要研究方向包括:新型脑功能影像、脑微观组织结构磁共振成像、 脑代谢成像、 中枢神经系统疾病诊断、脑中风诊断等。 脑影像技术研发属于交叉学科,热忱欢迎拥有神经生物学、生物医学工程、应用物理等背景并对科研有极大热情的同学加入。

二、工作内容

拟招聘的研究助理(技术员)岗位主要负责动物脑切片多模态成像(磁共振成像,荧光成像,电生理等)平台的搭建和科学研究,研究方向包括新型脑功能成像技术开发、脑中风成像方法研究等世界前沿问题。

岗位(1): 主要负责该多模态成像平台搭建和数据采集分析,包括磁共振成像序列编辑、荧光显微镜搭建、MATLAB数据分析等。

岗位(2): 主要负责该多模态成像平台中的生物模型,包括获取脑组织切片、细胞培养、神经元活动钙火花荧光成像等。

三、岗位要求

1、本科及以上学历。

2、对科学研究感兴趣;有上进心;对工作积极主动、认真负责;具有团队合作精神。

3、 岗位(1),具有应用物理、生物医学工程、光学、电子学等相关研究背景者优先。

4、岗位(2),具有神经生物学等相关研究背景者优先。

5、上岗时间九月底或十月初,能长期工作者或有读博意向者优先考虑。

四、联系方式:

有意者请将个人简历及求职信投递至bairuiliang@gmail.com(白瑞良老师)。 邮件主题请注明:“研究助理应聘+姓名”, 表明本人求职意向,并重点介绍本人的科研经历和专业技能及特长,符合要求者,我们将尽快安排面试,一经录用者,待遇从优。


2017-08-11 READ MORE

Positions for Principle Investigator

The Zhejiang University Interdisciplinary Institute of Neuroscience and Technology (ZIINT) is seeking faculty in systems neuroscience. ZIINT is a new center established at Zhejiang University to foster interdisciplinary interactions between neuroscience and other disciplines. This center will house 20 laboratories, a non-human primate facility, imaging center(3T and 7T machines) for both human and animal work, two-photon and microscopy facility, computing cluster, machine shop, and histological services.


Positions will be filled at the Assistant Professor, Associate Professor and Professor levels. Faculty research interests may include, but are not limited to, sensory and motor systems, cognition and decision making, emotional and social behavior, and development. We seek in particular candidates with strengths in non-human primate work, modern neurophysiological methods, computational neuroscience, molecular anatomical and viral techniques, neuroimaging, and neurotechnology. Successful candidates will have a strong publication record, excellent funding potential, and exceptional interest in collaborative, interdisciplinary efforts. Salaries and startup packages are competitive.


Philosophy: The future of brain science lies with integration of approaches from other scientific realms. Zhejiang's engineering strengths include biomedical engineering, optical engineering, nanotechnology, materials science, information sciences, and robotics. Zhejiang's world-class medical school features cutting edge research in cellular and molecular neuroscience. Translational efforts are supported by the Center for Translational Medicine and close ties with leading hospitals. Student quality is top notch. Zhejiang is an environment where diverse disciplines readily cross-foster.

Zhejiang University is located in Hangzhou, China (45 min bullet train from Shanghai). Home to beautiful West Lake, Hangzhou is a historical city, characterized by emphasis on cultural and environmental protection.


Applicants should submit inquiries, a curriculum vitae, research statement, and names of three references to ZIINT3@gmail.com.

2017-04-28 READ MORE

SHARED FACILITY

  • High Throughput Microscopy

  • Nonhuman Primate Facility

  • Highfield MRI

  • Two Photon Microscopy

  • Viral Vector Core

  • RF Coil

  • 3Dprinting and Machinng

  • Computer Cluster

THE TEAM

ABOUT US

The Zhejiang University Interdisciplinary Institute of Neuroscience and Technology (ZIINT) is a new center that fosters interdisciplinary interactions between neuroscience and other disciplines. This center is currently home to 15 laboratories, a non-human primate facility, two-photon and high throughput microscopy facility, viral vector core, computing cluster, machine shop, and histological services. It also features an MRI center for both human and animal work (Zhejiang University-Siemens Brain Imaging Research Center) which houses a 3T Prisma and 7T Magnetom, MR-compatible sensory stimulus presentation systems, human  MR-compatible EEG system, coil making facility, and animal support equipment.


Philosophy:The future of brain sciences lie with integration of approaches from other scientific realms. Zhejiang’s engineering strengths include biomedical engineering, optical engineering, nanotechnology, materials science, information sciences, and robotics. Zhejiang University’s world-class medical school features cutting edge research in cellular and molecular neuroscience. Translational efforts are supported by the Center for Translational Medicine and close ties with leading hospitals. Student quality is top notch. Zhejiang is an environment where diverse disciplines readily cross-foster.We are currently seeking investigators with interests in collaborative, cross-dsciplinary approaches.


ZIINT is located on the beautiful Hua Jia Chi campus, minutes from the famous West Lake, nature conservatories, and tea plantations of Hangzhou. Please feel free to contact us(ZIINT3@zju.edu.cn).

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